2021 International Conference on Nanotechnology and Applications (ICNA2021)

Prof. Bo Tan


Prof. Bo Tan

Ryerson University, Canada

Title: Ultrafast laser synthesis of 3D semiconductor nanostructure for SERS bio- sensing


Nanomaterials have been intensively researched to assist in molecular analysis. One such application is Surface Enhanced Raman Scattering (SERS), where nanomaterial is used to amplify the optical signal so that detection sensitivity detection can be extended to molecular level. Among various materials that have been research for SERS, semiconductors are of great interest to bio-chemical sensing. Compared to metals or organic materials, semiconductor nanomaterials are electrochemically stable and can be used in complex biochemical environments without substantial degradation. However, semiconductor nanomaterials suffer low amplification due to its poor conductivity. Using an ultrashort laser, our laboratory synthesized three-dimensional (3D) nanomaterials from Zinc oxides, silicon, nickel oxides and aluminum oxides. The building block of the 3D nanomaterials are particles less than 20 nm in size and rich in various atomic-scale defects.  The combination of quantum scale size, lattice vacancies and sophisticated 3D structure, gives rise to highly enhanced Raman signal. Various biomarkers and environmental contaminants were used to test these semiconductor nanomaterials’ sensitivity. Single molecular sensitivity has been demonstrated and the limit of detection is on par with gold/silver nanomaterial. We believe that the semiconductor nanomaterials synthesized through ultrashort laser hold the potential of expanding the scope and applicability of SERS in a broad range of applications.